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2021 | Spectrum | Volume 14 Number 6   9
                                                                                                  2020 | Spectrum | Volume 14 Number 6   9
        a role in KSD and alterations in the UMB may be a                                      Some of the posts, posted on social media were as
        risk factor for KSD. There may be a few key species                                   under:
        that give protection against stone disease, while, some
        phylotypes like Kalamiella piersonii MCC 3118 may
        facilitate the stone accumulation due to their specific
        metabolic pathways or modify the stone composition.












                                                   Participants

                                                   Total registration of 1700 + delegates. Online
                                                   participation of about 900+ on Day 01 and 700+ on
                                                   Day 02.  50 plus participants attended the symposium
                                                   physically.
                    Mangesh Suryavanshi
              (Yenepoya Research Centre, Mangalore)  Valedictory Session
          The third prize was awarded to Dr. Ankita Kumari  Panel Discussion
        (NATIONAL DAIRY RESEARCH INSTITUTE (NDRI),
        Karnal). She presented on “Probiotic Lactobacillus
        fermentum mediates its immunoregulatory function
        by targeting epigenomic modulations. The probiotic
        bacteria was isolated from the faeces of a 10-month-
        old infant had a role in gut homeostasis through the
        regulation of the immune response and could attenuate
        E.coli or LPS induced inflammatory response in
        intestinal epithelial cells.  The proposed mechanism
        was that L. fermentum regulated immune genes by
        activating HDAC1 which reduces H3 acetylation in
        a manner opposite to inflammatory which increases
        the levels of H3 acetylation by suppressing the mRNA
        expression of HDAC1.
          The regulation of immune genes by probiotics
        through epigenomic mechanisms further aided the
        existing understanding of cellular and molecular
        pathways that regulate host-commensal interactions.
        Panel Discussion







                                                          Dr. Neerja Hajela (General Secretary,
                                                          Gut Microbiota and Probiotic Science
                                                                Foundation (India)
                                                   Feedback
                                                     Most of the delegates rated the Symposium as
                                                   “Excellent” for all sessions.
                                                   Social Media
          The panel discussion was moderated by Prof.
        Anura Kurpad and the panel members were Prof.   Three social media platforms were created for the
        N.K. Ganguly, Prof. B.S. Ramakrishna, Prof. Anil   digital promotion of the symposium.
        Kumar Srivastava, Prof. J.B. Prajapati and Dr. B.   1. Facebook - https://www.facebook.com/11th-India-
        Sesikeran. The panel discussion highlighted the   Probiotic-Symposium-103923931757909/?ref=page_
        importance of the gut and its microbes in maintaining   internal
        the immune system. It also highlighted the role of
        the gut microbiome in chronic systemic inflammation   2. Instagram - https://www.instagram.com/
        and the role of probiotics in mitigating inflammation.   indiaprobioticsymposium/
        There was a discussion on real evidence for the use   3. LinkedIn - https://www.linkedin.com/in/india-
        of probiotics and the conditions where they may be   probiotic-symposium-b07a2a206/
        useful. The carrier matrix for delivery of a probiotic
        strain was discussed and the advantage of milk or   Regular posts were uploaded to encourage people
        fermented milk as a food matrix was highlighted. The   to register. Of the three platforms, LinkedIn got us
        difference between a probiotic food and traditional   the best results. The method adopted was to reach out
        fermented foods was clearly brought out.  The   to groups on Linked In and furnishing symposium
        myths surrounding A1 and A2 milk in terms of their   details on these groups. We filtered people on
        nutritional and health attributes were clarified. The   Linked Inn by location in India and targeted those
        panel discussion was highly interactive and very   who specialized in Biotechnology, Immunology
        well conducted.                            and Microbiology.
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